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11126 Sigma-Aldrich

Potassium antimonyl tartrate trihydrate

puriss., meets analytical specification of USP, 99.0-103.0%, powder

Synonym: Antimony potassium tartrate trihydrate, Tartar emetic

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Properties

Related Categories Essential Chemicals, Potassium Salts, Research Essentials, Salts
InChI Key   WBTCZEPSIIFINA-UHFFFAOYSA-J
grade   puriss.
assay   99.0-103.0%
form   powder
quality   meets analytical specification of USP
impurities   ≤0.02 mmol/g free acid
  ≤0.02 mmol/g free alkali
loss   ≤2.7% loss on drying, 105 °C
mp   ≥300 °C (lit.)
cation traces   As: ≤150 mg/kg
  Pb: ≤20 mg/kg

Description

General description

Potassium antimonyl tartrate trihydrate is a trivalent antimonial compound. It has been reported to be more toxic than pentavalent antimony (Pentostam) against Leishmania species. Its crystal structure has been investigated by the three-dimensional X-ray and white radiation neutron diffraction techniques. It crystallizes in space group C2221. Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.

Application

Potassium antimonyl tartrate trihydrate was employed as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum
It may also be used as a standard solution to determine the metalloid concentration such as Sb(III) and Sb(V) in surface soil, using high performance liquid chromatography coupled to inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 1551 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
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References

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