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14400 Sigma-Aldrich

Biotin

≥99.0% (T)

Synonym: D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

  • CAS Number 58-85-5

  • Empirical Formula (Hill Notation) C10H16N2O3S

  • Molecular Weight 244.31

  •  Beilstein/REAXYS Number 86838

  •  EC Number 200-399-3

  •  MDL number MFCD00005541

  •  eCl@ss 34058011

  •  PubChem Substance ID 329750287

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Properties

Related Categories Allium sativum (Garlic), Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C,
biological source   synthetic
InChI Key   YBJHBAHKTGYVGT-ZKWXMUAHSA-N
assay   ≥99.0% (T)
form   powder
optical activity   [α]20/D +91±2°, c = 1% in 0.1 M NaOH
application(s)   detection: suitable
ign. residue   ≤0.1% (as SO4)
loss   ≤0.5% loss on drying
color   colorless to white
mp   229-234 °C
  231-233 °C (lit.)
solubility   alcohol: soluble 80mg/100 ml at 25 °C
  water: soluble 22mg/100 ml at 25 °C
  0.1 M NaOH: 10 mg/mL at 25 °C, clear, colorless
  H2O: very soluble
  organic solvents: insoluble
cation traces   Ca: ≤50 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤10 mg/kg
  K: ≤50 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Na: ≤500 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Zn: ≤5 mg/kg

Description

Application

Biotin has been used for testing the functionality of the Avidin-displaying phages. The product has also been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

Biochem/physiol Actions

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Other Notes

Reviews; Avidin-Biotin technology;

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
XJ9088200

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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