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Daidzein

analytical standard

Synonym: 4′,7-Dihydroxy­iso­flavone, 7-Hydroxy-3-(4-hydroxy­phenyl)-4H-1-benzo­pyran-4-one, 7-Hydroxy-3-(4-hydroxy­phenyl)­chromone, Isoaurostatin

  • CAS Number 486-66-8

  • Empirical Formula (Hill Notation) C15H10O4

  • Molecular Weight 254.24

  •  Beilstein/REAXYS Number 231523

  •  EC Number 207-635-4

  •  MDL number MFCD00016954

  •  PubChem Substance ID 329751271

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Properties

Related Categories A - D, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography, Flavonoids,
grade   analytical standard
InChI Key   ZQSIJRDFPHDXIC-UHFFFAOYSA-N
assay   ≥97.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Food and Beverages
format   neat
storage temp.   2-8°C

Description

General description

Daidzein is an endocrine-active estrogenic isoflavone. This phytoestrogen is capable to bind to estrogen to exert estrogenic effects in vivo. It can naturally be found in soybean seed and flour.

Application

Daidzein was used as standard in determination of daidzein and genistein, in soybean food using in-tube solid-phase microextraction coupled to high-performance liquid chromatography (in-tube SPME–HPLC). It was also used as reference standard in determination of isoflavones in red clover using high-performance liquid chromatography–UV–electrospray ionization-mass spectrometric detector (HPLC–UV–ESI-MSD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

10 mg in glass bottle

Biochem/physiol Actions

Soy isoflavone daidzein protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DJ3100040

Documents

Certificate of Analysis

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Protocols & Articles

Articles

HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 1)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 1)
Keywords: Chromatography, High performance liquid chromatography, Hormones, Separation

HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 2)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 2)
Keywords: Chromatography, High performance liquid chromatography, Hormones, Separation

HPLC Analysis of Isoflavones on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Isoflavones on Ascentis® Phenyl
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Vitamins

LC/MS Analysis of Isoflavones on Chromolith® FastGradient RP-18 endcapped

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Isoflavones on Chromolith® FastGradient RP-18 endcapped
Keywords: Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry

Peer-Reviewed Papers
15

References

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