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Acrylamide

analytical standard

Synonym: 2-Propenamide, Acrylic acid amide

  • CAS Number 79-06-1

  • Linear Formula CH2=CHCONH2

  • Molecular Weight 71.08

  •  Beilstein/REAXYS Number 605349

  •  EC Number 201-173-7

  •  MDL number MFCD00008032

  •  eCl@ss 39031205

  •  PubChem Substance ID 329752440

  •  NACRES NA.24

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Properties

Related Categories A-B, A-C, Additional Standards, Aliphatics, Alpha Sort,
Quality Level   100
grade   analytical standard
vapor density   2.45 (vs air)
vapor pressure   0.03 mmHg ( 40 °C)
assay   ≥99.0% (GC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
bp   125 °C/25 mmHg (lit.)
mp   82-86 °C (lit.)
solubility   water: soluble 200 g/L at 20 °C
Featured Industry   Cleaning Products
Cosmetics
Environmental
Food and Beverages
Personal Care
format   neat
SMILES string   NC(=O)C=C
InChI   1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
InChI key   HRPVXLWXLXDGHG-UHFFFAOYSA-N

Description

General description

Acrylamide is a colorless, odorless, vinyl monomer formed from the hydration of acrylonitrile. It is a highly water soluble crystalline amide that polymerizes and forms a byproduct during the heating of starch-rich foods to high temperatures. Mostly used in the production of polymers mainly in the water treatment industry, pulp and paper industry and textile treatment industry and is used as a laboratory reagent. Acrylamide can act as a human carcinogen. It has a reactive double bond and an amide group.

Application

Acrylamide may be used as an analytical reference standard for the determination of the analyte in:
• Environmental water samples using ion-exclusion chromatography-mass spectrometry system (IEC-MS).
• Cereal-based food products by gas chromatography coupled to mass spectrometry (GC–MS) and reversed phase-high performance liquid chromatography with diode array detection (RP-HPLC-DAD).
• Potato-based foods by liquid chromatography with diode array detection (LC–DAD).

Refer to the products certificate of analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
RIDADR 
UN 2074 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
AS3325000
Flash Point(F) 
280.4 °F - closed cup
Flash Point(C) 
138 °C - closed cup
Protocols & Articles

Articles

HPLC Analysis of Acrylamide and Acrylic Acid on Discovery® HS F5

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Acrylamide and Acrylic Acid on Discovery® HS F5
Keywords: Chromatography, High performance liquid chromatography

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Peer-Reviewed Papers
15

References

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