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242845 Sigma-Aldrich

Acetic anhydride

ACS reagent, ≥98.0%

  • CAS Number 108-24-7

  • Linear Formula (CH3CO)2O

  • Molecular Weight 102.09

  •  Beilstein Registry Number 385737

  •  EC Number 203-564-8

  •  MDL number MFCD00008705

  •  PubChem Substance ID 24854587

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Carboxylic Acid Anhydrides, Chemical Synthesis, Organic Building Blocks More...
grade   ACS reagent
vapor density   3.5 (vs air)
vapor pressure   10 mmHg ( 36 °C)
  4 mmHg ( 20 °C)
InChI Key   WFDIJRYMOXRFFG-UHFFFAOYSA-N
assay   ≥98.0%
autoignition temp.   629 °F
expl. lim.   10.3 %
impurities   MnO4- reducers, passes test
evapn. residue   ≤0.003%
refractive index   n20/D 1.390(lit.)
bp   138-140 °C(lit.)
mp   −73 °C (lit.)
solubility   H2O: slightly soluble
density   1.08 g/mL(lit.)
anion traces   chloride (Cl-): ≤5 ppm
  phosphate (PO43-): ≤0.001%
  sulfate (SO42-): ≤5 ppm
cation traces   Fe: ≤5 ppm
  heavy metals: ≤2 ppm

Description

Packaging

1, 6×1, 3 kg in glass bottle

5, 100, 4×100 g in glass bottle

Application

Acetic anhydride has been used as one of the reaction components in the preparation of:
• 2-acetylamino-5-aminobenzenesulfonic acid
• 3,3′-bis(sulfonato)-4,4′-bis(chloroacetamido)azobenzene (BSBCA)
• 10-acetoxy-9-nitro-octadecanoic acid, allyl ester
• 9-nitro-oleic acid
It may be used for acetylation of anisole over HBEA zeolite in a batch reactor.

General description

Acetic anhydride is an organic solvent. On dissolution in water it undergoes solvolysis to afford acetic acid. It is widely employed for the acetylation of various alcohols. Wacher process (starting reagent + a ketene) and Knapsack process (starting reagent = acetaldehyde) have been reported for the industrial preparation of acetic anhydride.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1715 3(8) / PGII
WGK Germany 
1
RTECS 
AK1925000
Flash Point(F) 
120.2 °F
Flash Point(C) 
49 °C

Documents

Certificate of Analysis

Certificate of Origin


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Peer-Reviewed Papers
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References

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