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247588 Sigma-Aldrich

Salicylic acid

ACS reagent, ≥99.0%

Synonym: 2-Hydroxybenzoic acid

  • CAS Number 69-72-7

  • Linear Formula 2-(HO)C6H4CO2H

  • Molecular Weight 138.12

  •  Beilstein/REAXYS Number 774890

  •  EC Number 200-712-3

  •  MDL number MFCD00002439

  •  PubChem Substance ID 24854876

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Properties

Related Categories Acids, Acids & Bases, Aromatic Compounds, Building Blocks, C7,
Quality Level   200
grade   ACS reagent
vapor density   4.8 (vs air)
vapor pressure   1 mmHg ( 114 °C)
assay   ≥99.0%
impurities   H2SO4, passes test (darkened)
ign. residue   ≤0.01%
bp   211 °C (lit.)
mp   158-161 °C (lit.)
anion traces   chloride (Cl-): ≤0.001%
  sulfate (SO42-): ≤0.003%
cation traces   Fe: ≤2 ppm
  heavy metals (as Pb): ≤5 ppm
SMILES string   OC(=O)c1ccccc1O
InChI   1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChI key   YGSDEFSMJLZEOE-UHFFFAOYSA-N
Gene Information   human ... ALB(213), PTPN1(5770)

Description

General description

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

Application

Salicylic acid has been used:
• to study its antimicrobial effect in vitro and in situ against Penicillium expansum
• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Packaging

100, 500 g in poly bottle

Biochem/physiol Actions

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as, seed germination, seedling establishment, cell growth, respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
VO0525000
Flash Point(F) 
314.6 °F
Flash Point(C) 
157 °C

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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