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282820 Sigma-Aldrich

Protoporphyrin IX zinc(II)

guanylate cyclase inhibitor

Synonym: 3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid, 8,13-Divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid zinc derivative, Protoporphyrin IX zinc(II) complex

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Properties

Related Categories Materials Science, Organic and Printed Electronics, Photonic and Optical Materials, Phthalocyanine and Porphyrin Dyes, Porphyrines More...
Quality Level   100
assay   ≥92% (HPLC)
form   powder
application(s)   hematology: suitable
  histology: suitable
λmax   426 nm
ε (extinction coefficient)   ≥10000 at 585-591 nm in pyridine
  ≥12000 at 548-554 nm in pyridine
  ≥135000 at 423-429 nm in pyridine
Featured Industry   Diagnostic Assay Manufacturing
storage temp.   room temp
SMILES string   Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Zn]n34)c(C=C)c5C
InChI   1S/C34H34N4O4.Zn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;
InChI key   FUTVBRXUIKZACV-RGGAHWMASA-L

Description

General description

Protoporphyrin IX zinc(II) (ZnPP) is an anti-oxidant enzyme heme oxygenase-1.

Application

Cellular melanin content in normal human melanocytes treated with ZnPP has been studied. 1 It was used as a standard in a study where the excess formation of ZnPP in iron deficient erythropoiesis was determined by haematofluorometer.

Inhibits soluble guanylate cyclase.

Packaging

50, 250 mg in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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