EMAIL THIS PAGE TO A FRIEND
288306 Sigma-Aldrich

Chloroform

anhydrous, ≥99%, contains 0.5-1.0% ethanol as stabilizer

Synonym: Methylidyne trichloride, Trichloromethane

  • CAS Number 67-66-3

  • Empirical Formula (Hill Notation) CHCl3

  • Molecular Weight 119.38

  •  Beilstein/REAXYS Number 1731042

  •  MDL number MFCD00000826

  •  PubChem Substance ID 57648332

  •  NACRES NA.21

Purchase

Properties

Related Categories Anhydrous Solvents, Chloroform, Solvent by Type, Solvent Bottles, Solvent Packaging Options,
Quality Level   100
grade   anhydrous
vapor density   4.1 (vs air)
vapor pressure   160 mmHg ( 20 °C)
assay   ≥99%
contains   0.5-1.0% ethanol as stabilizer
packaging   Sure/Seal of 1, 2 L
  Sure/Seal of 100, 12x100 mL
impurities   <0.001% water
  <0.005% water (100 mL pkg)
evapn. residue   <0.0003%
color   colorless
refractive index   n20/D 1.445 (lit.)
bp   60.5-61.5 °C (lit.)
mp   −63 °C (lit.)
density   1.48 g/mL at 25 °C
  1.492 g/mL at 25 °C (lit.)
SMILES string   ClC(Cl)Cl
InChI   1S/CHCl3/c2-1(3)4/h1H
InChI key   HEDRZPFGACZZDS-UHFFFAOYSA-N

Description

General description

Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. Due to its light sensitivity, it may undergo degradation with time. This can be suppressed by adding ethanol as a stabilizer. The addition will increase the polarity of the solvent and potentially impact certain applications.

Application

Chloroform has been used as a solvent for dissolving lipids and also as a cleansing agent. It may also be used in solvent extraction process and also for recrystallization.

Packaging

1, 2 L in Sure/Seal™

100, 12×100 mL in Sure/Seal™

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Central nervous system
RIDADR 
UN 1888 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
does not flash
Flash Point(C) 
does not flash

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Articles

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Related Content

Lab Chemicals

We are a leading global supplier and manufacturer of high-quality, stockroom and basic research products including solvents, acids and inorganics. We specialize in providing the most comprehensive pr...
Keywords: Solvents

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?