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288306 Sigma-Aldrich

Chloroform

anhydrous, ≥99%, contains 0.5-1.0% ethanol as stabilizer

Synonym: Methylidyne trichloride, Trichloromethane

  • CAS Number 67-66-3

  • Empirical Formula (Hill Notation) CHCl3

  • Molecular Weight 119.38

  •  Beilstein/REAXYS Number 1731042

  •  MDL number MFCD00000826

  •  PubChem Substance ID 57648332

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Properties

Related Categories Anhydrous Solvents, Chloroform, Solvent by Type, Solvent Bottles, Solvent Packaging Options,
grade   anhydrous
vapor density   4.1 (vs air)
vapor pressure   160 mmHg ( 20 °C)
InChI Key   HEDRZPFGACZZDS-UHFFFAOYSA-N
assay   ≥99%
contains   0.5-1.0% ethanol as stabilizer
packaging   Sure/Seal of 1, 2 L
  Sure/Seal of 100, 12x100 mL
impurities   <0.001% water
  <0.005% water (100 mL pkg)
evapn. residue   <0.0003%
color   colorless
refractive index   n20/D 1.445 (lit.)
bp   60.5-61.5 °C(lit.)
mp   −63 °C (lit.)
density   1.48 g/mL at 25 °C
  1.492 g/mL at 25 °C (lit.)

Description

General description

Chloroform is a volatile chlorinated organic solvent whose vapors have a narcotic effect. Due to its light sensitivity, it may undergo degradation with time. This can be suppressed by adding ethanol as a stabilizer. The addition will increase the polarity of the solvent and potentially impact certain applications.

Application

Chloroform has been used as a solvent for dissolving lipids and also as a cleansing agent. It may also be used in solvent extraction process and also for recrystallization.

Packaging

1, 2 L in Sure/Seal™

100, 12×100 mL in Sure/Seal™

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
RIDADR 
UN 1888 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

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Peer-Reviewed Papers
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References

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