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30080 Sigma-Aldrich

Cysteamine hydrochloride

≥97.0% (RT)

Synonym: β-Mercapto­ethylamine hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, 2-Amino­ethane­thiol hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

  • CAS Number 156-57-0

  • Linear Formula HSCH2CH2NH2 · HCl

  • Molecular Weight 113.61

  •  Beilstein/REAXYS Number 3590083

  •  EC Number 205-858-1

  •  MDL number MFCD00012904

  •  PubChem Substance ID 329753425

  •  NACRES NA.51

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Properties

Related Categories Building Blocks, Chemical Synthesis, Organic Building Blocks, Sulfur Compounds, Thiol/Mercaptan Salts More...
Quality Level   200
assay   ≥97.0% (RT)
mp   64-70 °C
  67-71 °C
storage temp.   2-8°C
SMILES string   Cl[H].NCCS
InChI   1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H
InChI key   OGMADIBCHLQMIP-UHFFFAOYSA-N

Description

Application

Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-.

Biochem/physiol Actions

Cysteamine hydrochloride is derived from the degradation of coenzyme A endogenously. Its concentration in plasma is low. It is commonly used as a drug for the orphan disease cystinosis, a lysosomal storage disorder, in which cysteamine decreases intralysosomal cystine accumulation.

Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 3335
WGK Germany 
WGK 3
RTECS 
KJ0200000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles
Peer-Reviewed Papers
15

References

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