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31493 Sigma-Aldrich

Sodium salicylate

puriss. p.a., Reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Synonym: 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

  • CAS Number 54-21-7

  • Linear Formula HOC6H4COONa

  • Molecular Weight 160.10

  •  Beilstein/REAXYS Number 3732792

  •  EC Number 200-198-0

  •  MDL number MFCD00002440

  •  PubChem Substance ID 57648580

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Properties

Related Categories Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography, Essential Chemicals, Puriss p.a.,
grade   Reag. Ph. Eur.
InChI Key   ABBQHOQBGMUPJH-UHFFFAOYSA-M
grade   puriss. p.a.
assay   99.5-101.0% (calc. to the dried substance)
impurities   acidic reac. impurities, complies
  sulfite or thiosulfate, complies
  ≤0.001% heavy metals (as Pb)
loss   ≤0.3% loss on drying, 105 °C
mp   >300 °C (lit.)
anion traces   chloride (Cl-): ≤20 mg/kg
  sulfate (SO42-): ≤500 mg/kg
cation traces   Fe: ≤10 mg/kg
suitability   in accordance for appearance of solution

Description

General description

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.

Application

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia. It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from the mixed micelles [composed of Pluronic P105 (P105) and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)].

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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