324558 Sigma-Aldrich

Ethylene glycol

anhydrous, 99.8%

Synonym: 1,2-Ethanediol

  • CAS Number 107-21-1

  • Linear Formula HOCH2CH2OH

  • Molecular Weight 62.07

  •  Beilstein/REAXYS Number 505945

  •  EC Number 203-473-3

  •  MDL number MFCD00002885

  •  eCl@ss 39020501

  •  PubChem Substance ID 57648687

  •  NACRES NA.21



Related Categories Anhydrous Solvents, Chemical Synthesis, Other Protecting and Derivatizing Reagents, Protecting and Derivatizing Reagents, Protection and Derivatization,
Quality Level   100
grade   anhydrous
vapor density   2.1 (vs air)
vapor pressure   0.08 mmHg ( 20 °C)
assay   99.8%
form   liquid
autoignition temp.   752 °F
expl. lim.   15.3 %
impurities   <0.003% water
  <0.005% water (100 mL pkg)
refractive index   n20/D 1.431 (lit.)
bp   195-198 °C
mp   −13 °C (lit.)
density   1.113 g/mL at 25 °C (lit.)
SMILES string   OCCO
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2


General description

Ethylene glycol is the major component of antifreeze preparations.


Ethylene glycol may be used in the preparation of spiroborate esters by reacting with chiral 1,2-aminoalcohols in the presence of triisopropyl borate. It may also be used as a solvent in the preparation of tris(2,2′-bipyrazyl)ruthenium(II) chloride by the reaction of 2,2′-bipyrazine with ruthenium(III) chloride.


1, 6×1, 2 L in Sure/Seal™

100 mL in Sure/Seal™

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 324558.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
Target organs 
UN 3082 9 / PGIII
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the molarity of ethylene glycol?
Ethylene glycol is 17.93M. This is calculated using the density (1.113 g/ml) and the molecular weight (62.07 g/mol). If the product is less than 100% pure,correct for the purity.
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