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Metoclopramide

VETRANAL, analytical standard

Synonym: 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Methoxychloroprocainamide

  • CAS Number 364-62-5

  • Empirical Formula (Hill Notation) C14H22ClN3O2

  • Molecular Weight 299.80

  •  Beilstein/REAXYS Number 1884366

  •  EC Number 206-662-9

  •  MDL number MFCD00211338

  •  PubChem Substance ID 329754232

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Properties

Related Categories Additional Drugs, Analytical Standards, Analytical/Chromatography, Pharmaceuticals, Illicit Drugs & Alcohol
grade   analytical standard
InChI Key   TTWJBBZEZQICBI-UHFFFAOYSA-N
product line   VETRANAL
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Pharmaceutical (small molecule)
format   neat
storage temp.   2-8°C

Description

General description

Metoclopramide is typically employed as an antiemetic drug or a gastrointestinal prokinetic drug in adults and children.

Application

Metoclopramide may be used as an analytical reference standard for the determination of the analyte in:
• Human plasma by liquid–liquid extraction (LLE) with dichloromethane followed by hydrophilic interaction chromatography-electrospray iionization-tandem mass spectrometry (HILIC-ESI-MS/MS) operating in selected reaction monitoring (SRM) mode of detection.

It may also be used as an internal standard for the determination of loratadine and desloratadine in:
• Human plasma by high performance liquid chromatography (HPLC) coupled to MS/MS with multiple reaction monitoring (MRM) detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a trademark of Sigma-Aldrich Chemie GmbH

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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