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Patulin

reference material

Synonym: 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one

  • CAS Number 149-29-1

  • Empirical Formula (Hill Notation) C7H6O4

  • Molecular Weight 154.12

  •  Beilstein Registry Number 149675

  •  EC Number 205-735-2

  •  MDL number MFCD00005858

  •  PubChem Substance ID 329754321

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Properties

Related Categories All alphabetically sorted, Analytical Standards, Analytical/Chromatography, Biotoxin and Mycotoxin Standards, Food and Cosmetic Component Standards,
grade   analytical standard
  reference material
InChI Key   ZRWPUFFVAOMMNM-UHFFFAOYSA-N
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Cosmetics, Personal Care, and Cleaning Products
Food and Beverages
format   neat
storage temp.   −20°C

Description

Application

PAT may be used as a reference standard for the determination of patulin in:
• Fruit-based products by QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method and solid phase extraction (SPE) followed by analysis using ultra-high performance liquid chromatography combined with electrospray ionization tandem mass spectrometry (UHPLC-ESI-MS/MS).
• Apple juice samples by single drop liquid-liquid-liquid microextraction (SD-LLLME) followed by LC-MS/MS analysis.
• Model food matrices by “dilute and shoot” LC-MS/MS.
• Dairy products by QuEChERS procedure and UHPLC-ESI quadrupole orbitrap (Q-Orbitrap) mass spectrometry.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Patulin (PAT) is a mycotoxin of the polyketide lactone type, usually produced by species of the Penicillium, Aspergillus and Byssochlamys genera.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGII
WGK Germany 
3
RTECS 
LV2625000
Protocols & Articles

Articles

Better Tools for Fast and Convenient Patulin Analysis

The mycotoxin patulin is often found in rotten apples. It is mostly produced by Aspergillus, Penicillium and Byssochlamys and shows a variety of short-term and long-term effects in animal studies, ra...
Eva Katharina Richter, Christine Dumas
Keywords: Gastrointestinal, High performance liquid chromatography, Phase transitions, Purification, Sample preparations, Separation, Solid phase extractions

TLC Analysis Report of Cholesterol and its Bile Acid Metabolites on HPTLC Pre-Coated Plate RP-18 F254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis Report of Cholesterol and its Bile Acid Metabolites on HPTLC Pre-Coated Plate RP-18 F254s
Keywords: Chromatography, Thin layer chromatography

TLC Analysis of Mycotoxins on HPTLC Silica 60F 254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Mycotoxins on HPTLC Silica 60F 254s
Keywords: Agriculture, Thin layer chromatography

TLC Analysis of Mycotoxins on HPTLC Silica Gel 60 RP-8 WF254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Mycotoxins on HPTLC Silica Gel 60 RP-8 WF254s
Keywords: Chromatography, Thin layer chromatography

TLC Analysis of Mycotoxins on HPTLC pre-coated plate RP-8 F254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Mycotoxins on HPTLC pre-coated plate RP-8 F254s
Keywords: Chromatography, Thin layer chromatography

UHPLC Analysis of Patulin in Cloudy Apple Cider on Titan™ C18 following SPE using SupelMIP® SPE - Patulin

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Patulin in Cloudy Apple Cider on Titan™ C18 following SPE using SupelMIP® SPE - Patulin
Keywords: Centrifugation, Chromatography, Sample preparations, Separation, Solid phase extractions, Solvents, Sonication

Peer-Reviewed Papers
15

References

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