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33154 Sigma-Aldrich

Dithizone

puriss. p.a., Reag. Ph. Eur., ≥98% (chelatometric), for metal titration

Synonym: Diphenylthiocarbazone

  • CAS Number 60-10-6

  • Linear Formula C6H5NHNHCSN=NC6H5

  • Molecular Weight 256.33

  •  Beilstein/REAXYS Number 748838

  •  EC Number 200-454-1

  •  MDL number MFCD00003025

  •  PubChem Substance ID 329754465

  •  NACRES NA.21

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Properties

Related Categories Analytical Reagents, Analytical Standards, Analytical/Chromatography, Extractables and Leachables, Food & Beverage Standards,
Quality Level   200
grade   Reag. Ph. Eur.
  puriss. p.a.
assay   ≥98% (chelatometric)
application(s)   titration: suitable
impurities   ≤0.001% heavy metals (as Pb)
ign. residue   ≤0.2% (as SO4)
mp   168 °C (dec.) (lit.)
absorption   ≥1450 at 605 nm
SMILES string   S=C(NNc1ccccc1)\N=N\c2ccccc2
InChI   1S/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+
InChI key   UOFGSWVZMUXXIY-BMRADRMJSA-N

Description

General description

Dithizone (Diphenylthiocarbazone) is used as chelating agent for zinc. It is widely used for the liquid-liquid and solid phase extraction of various metals since it forms stable complexes with the metals.

Application

Dithizone (Diphenylthiocarbazone) may be used for the in vitro characterization of differentiated pancreatic islets clusters in differentiated embryonic stem cell cultures, as it forms chelates with zinc present in huge quantities in pancreatic islets, thereby selectively staining them. It may be used to form complex with silver ions in the cloud point preconcentration step before the trace level quantification of silver by flame atomic absorption spectrometry.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
LQ9450000

Documents

Certificate of Analysis (COA)

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Titrette from Brand
Protocols & Articles
Peer-Reviewed Papers
15

References

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