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33429 Supelco

Doxycycline hyclate

VETRANAL, analytical standard

Synonym: Doxycycline hydrochloride hemiethanolate hemihydrate

  • CAS Number 24390-14-5

  • Empirical Formula (Hill Notation) C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O

  • Molecular Weight 512.94

  •  Beilstein Registry Number 5702728

  •  MDL number MFCD07357237

  •  PubChem Substance ID 329754541

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Properties

Related Categories 1694 Pharmaceuticals & Personal Care Products, A - K, Additional Standards, Analytical Standards, Analytical/Chromatography,
grade   analytical standard
InChI Key   HALQELOKLVRWRI-ZVACAFRPSA-N
product line   VETRANAL
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
solubility   DMSO: soluble 100 mM
Agency/Method   EPA 1694
Featured Industry   Environmental
Pharmaceutical (small molecule)
Mode of action   protein synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  mycoplasma
  parasites
format   neat

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.

General description

Chemical structure: tetracycline

Legal Information

VETRANAL is a trademark of Sigma-Aldrich Chemie GmbH

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
QI8925000

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Is doxycycline hyclate soluble in DMSO?
According to literature sources, doxycycline hyclate is soluble in DMSO at a concentration of 100 mM.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
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Protocols & Articles

Articles

LC/MS/MS Analysis of Tetracycline Antibiotics on Kromasil® Eternity™ C18

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Tetracycline Antibiotics on Kromasil® Eternity™ C18
Keywords: Antibiotics, Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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