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33515 Sigma-Aldrich

6-Diazo-5-oxo-L-norleucine

≥98.0% (UV)

Synonym: (S)-2-Amino-6-diazo-5-oxocaproic acid, DON

  • CAS Number 157-03-9

  • Empirical Formula (Hill Notation) C6H9N3O3

  • Molecular Weight 171.15

  •  Beilstein/REAXYS Number 1725815

  •  MDL number MFCD00037218

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Properties

assay   ≥98.0% (UV)
mp   ~145 °C (dec.)
Mode of action   enzyme | inhibits
storage temp.   −20°C
SMILES string   N[C@@H](CCC(=O)C=[N+]=[N-])C(O)=O
InChI   1S/C6H9N3O3/c7-5(6(11)12)2-1-4(10)3-9-8/h3,5H,1-2,7H2,(H,11,12)/t5-/m0/s1
InChI key   YCWQAMGASJSUIP-YFKPBYRVSA-N

Description

General description

Chemical structure: amino acid derivatives

Application

Inhibits purine synthesis. An analogue of glutamine, inhibiting glutamine-requiring enzymes.

Safety & Documentation

Safety Information

RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
RC6340000

Documents

Certificate of Analysis (COA)

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D2141 6-Diazo-5-oxo-L-norleucine, crystalline

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