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Flunixin

VETRANAL®, analytical standard

Synonym: 2-[2-Methyl-3-(trifluoromethyl)phenylamino]nicotinic acid

  • CAS Number 38677-85-9

  • Empirical Formula (Hill Notation) C14H11F3N2O2

  • Molecular Weight 296.24

  •  MDL number MFCD00072033

  •  PubChem Substance ID 329754590

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Life Sciences Standards,
Quality Level   100
grade   analytical standard
product line   VETRANAL®
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Forensics and Toxicology
Pharmaceutical (small molecule)
format   neat
SMILES string   Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F
InChI   1S/C14H11F3N2O2/c1-8-10(14(15,16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,21)
InChI key   NOOCSNJCXJYGPE-UHFFFAOYSA-N

Description

General description

Flunixin is a potent nonsteroidal anti-inflammatory drug, primarily used as an anti-inflammatory agent and analgesic for the short-term treatment of moderate pain and inflammation in farm animals. It is also effective in inhibiting the synthesis of prostaglandins.

Flunixin is classified under the group of non-steroidal anti-inflammatory drugs (NSAIDs).

Application

Flunixin may be used as a reference standard for the determination of NSAID drug, flunixin in biological samples using high-performance liquid chromatography with diode array detection (HPLC-DAD)/particle beam mass spectrometry (PB-MS)/atmospheric pressure ionization mass spectrometry (API-MS) and gas chromatography coupled to mass spectrometry (GC-MS).

Flunixin may be used as an analytical reference standard for the determination of flunixin in:
• Bovine muscle samples by hydrophilic interaction liquid chromatography-electrospray-tandem mass spectrometry (HILIC-ESI-MS/MS) equipped with selected reaction monitoring (SRM) detection.
• Animal tissues by dispersive-solid phase extraction (d-SPE) and enhanced matrix removal for lipids (EMR-L), followed by analysis using ultra-high performance liquid chromatography-triple quadrupole or quadrupole-time-of-flight (UHPLC-QqQ or UHPLC-Q/TOF) methods in conjunction with ESI-MS/MS operating on multiple reaction monitoring (MRM) mode of detection as well as ESI-LC-MS/MS with SRM detection mode.
• Porcine muscle samples by ESI-LC-MS/MS with MRM detection mode.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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