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365548 Sigma-Aldrich

Direct Red 80

Dye content 25 %

Synonym: Sirius Red

  • CAS Number 2610-10-8

  • Empirical Formula (Hill Notation) C45H26N10Na6O21S6

  • Molecular Weight 1373.07

  •  Colour Index Number 35780

  •  Beilstein/REAXYS Number 8185575

  •  EC Number 220-027-3

  •  MDL number MFCD00054389

  •  PubChem Substance ID 24862536

  •  NACRES NA.47

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Properties

Related Categories Cell Biology, D, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes More...
Quality Level   200
form   powder
composition   Dye content, 25%
λmax   528 nm
ε (extinction coefficient)   ≥12000 at 277-283 nm in H2O
  ≥15000 at 223-235 nm in H2O
  ≥32000 at 524-530 nm in H2O
SMILES string   [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].Oc1c(\N=N\c2ccc(cc2S([O-])(=O)=O)\N=N\c3ccc(cc3)S([O-])(=O)=O)c(cc4cc(NC(=O)Nc5ccc6c(O)c(\N=N\c7ccc(cc7S([O-])(=O)=O)\N=N\c8ccc(cc8)S([O-])(=O)=O)c(cc6c5)S([O-])(=O)=O)ccc14)S([O-])(=O)=O
InChI   1S/C45H32N10O21S6.6Na/c56-43-33-13-5-27(17-23(33)19-39(81(71,72)73)41(43)54-52-35-15-7-29(21-37(35)79(65,66)67)50-48-25-1-9-31(10-2-25)77(59,60)61)46-45(58)47-28-6-14-34-24(18-28)20-40(82(74,75)76)42(44(34)57)55-53-36-16-8-30(22-38(36)80(68,69)70)51-49-26-3-11-32(12-4-26)78(62,63)64;;;;;;/h1-22,56-57H,(H2,46,47,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76);;;;;;/q;6*+1/p-6/b50-48+,51-49+,54-52+,55-53+;;;;;;
InChI key   YIQKLZYTHXTDDT-IJPLDVMMSA-H

Description

General description

Direct Red 80 is a tetra azo dye. It is also known as sirius red F3BA, sirius red F3B etc. It can be used to detect amyloid. It can magnify the usual birefringence of collagen fibers in tissue sections.

Application

Direct Red 80 has been used as an ingredient in the preparation of saturated picric acid for immunohistochemical detection and quantitation of collagen in liver tissues. It has also been used in the staining for collagen.

Packaging

5, 25 g in glass bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

A Novel 3D Perfusion Bioreactor

Qing Liu, Ph.D., is an expert in biomaterials, tissue engineering, and in vitro tissue model for drug screening. Carlos E. Caicedo-Carvajal, Ph.D., has worked in several areas of Biomedical Engineeri...
Carlos E. Caicedo-Carvajal, Ph.D.; Qing Liu, Ph.D.
Biowire Spring 2012, 25–28
Keywords: Adhesion, Biomaterials, Cancer, Cell culture, Cell proliferation, Deposition, Gene expression, Nutrition, Size-exclusion chromatography

Peer-Reviewed Papers
15

References

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