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4-Aminopyridine

PESTANAL®, analytical standard

Synonym: 4-Pyridinamine, 4-Pyridylamine, 4AP, Fampridine

  • CAS Number 504-24-5

  • Empirical Formula (Hill Notation) C5H6N2

  • Molecular Weight 94.11

  •  Beilstein/REAXYS Number 105782

  •  EC Number 207-987-9

  •  MDL number MFCD00006439

  •  PubChem Substance ID 329755452

  •  NACRES NA.24

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Properties

Related Categories A-B, Additional Standards, Alpha Index of All Pesticide Standards, Amines, Analytical Standards,
Quality Level   100
grade   analytical standard
product line   PESTANAL®
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
bp   273 °C (lit.)
mp   155-158 °C (lit.)
Featured Industry   Agriculture
Environmental
format   neat
SMILES string   Nc1ccncc1
InChI   1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChI key   NUKYPUAOHBNCPY-UHFFFAOYSA-N
Gene Information   human ... KCNA1(3736), KCNA10(3744), KCNA2(3737), KCNA3(3738), KCNA4(3739), KCNA5(3741), KCNA6(3742), KCNA7(3743), KCNB1(3745), KCNB2(9312), KCNC1(3746), KCNC2(3747), KCNC3(3748), KCNC4(3749), KCND1(3750), KCND2(3751), KCND3(3752), KCNF1(3754), KCNG1(3755), KCNG2(26251), KCNG3(170850), KCNG4(93107), KCNH1(3756), KCNH2(3757), KCNH3(23416), KCNH4(23415), KCNH5(27133), KCNH6(81033), KCNH7(90134), KCNH8(131096), KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479), KCNS1(3787), KCNS2(3788), KCNS3(3790), KCNV1(27012), KCNV2(169522)

Description

General description

4-Aminopyridine is a small molecule potassium channel blocker, which stimulates the release of glutamate from nerve terminals and induces seizures. It can also be used as a drug that aims to improve ambulatory impairment, a major symptom of multiple sclerosis disease.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2671 6.1 / PGII
WGK Germany 
WGK 3
RTECS 
US1750000
Flash Point(F) 
312.8 °F
Flash Point(C) 
156 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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