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383376 Sigma-Aldrich

Potassium antimonyl tartrate trihydrate

ACS reagent, ≥99%

Synonym: Antimony potassium tartrate trihydrate, Tartar emetic

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Properties

Related Categories Asymmetric Synthesis, Carboxylic Acid Salts, Chemical Synthesis, Chiral Building Blocks, Essential Chemicals,
grade   ACS reagent
InChI Key   WBTCZEPSIIFINA-UHFFFAOYSA-J
assay   ≥99%
  99.0-103.0%
impurities   ≤0.020 meq/g Titr. acid or base
loss   ≤2.7% loss on drying
mp   ≥300 °C (lit.)
solubility   water: soluble
cation traces   As: ≤0.015%

Description

General description

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

Application

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.

Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.

Packaging

100 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 1551 6.1 / PGIII
WGK Germany 
3
RTECS 
CC6825000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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