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Isorhamnetin

analytical standard

Synonym: 3′-Methoxy-3,4′,5,7-tetrahydroxyflavone, 3′-Methylquercetin, 3,4′,5,7-Tetrahydroxy 3′-methoxyflavone, Isorhamnetol, Quercetin 3′-methyl ether

  • CAS Number 480-19-3

  • Empirical Formula (Hill Notation) C16H12O7

  • Molecular Weight 316.26

  •  Beilstein/REAXYS Number 44723

  •  EC Number 207-545-5

  •  MDL number MFCD00017310

  •  PubChem Substance ID 329755802

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography, Calendula,
Quality Level   100
grade   analytical standard
assay   ≥99% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Food and Beverages
format   neat
storage temp.   2-8°C
SMILES string   COc1cc(ccc1O)C2=C(O)C(=O)c3c(O)cc(O)cc3O2
InChI   1S/C16H12O7/c1-22-11-4-7(2-3-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3
InChI key   IZQSVPBOUDKVDZ-UHFFFAOYSA-N

Description

General description

Isorhamnetin belongs to the flavonoids class of compounds.

Application

Isorhamnetin may be used as an analytical reference standard for the determination of isorhamnetin in:
• Rat plasma samples by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
• Lotus (Nelumbo nucifera) leaves by macroporous resin chromatography combined with HPLC-ESI-MS/MS.
• Powdered extracts and finished products samples of Ginkgo biloba by HPLC-MS.
• Human plasma and urine by high-throughput micro solid-phase extraction (μ-SPE), followed by analysis using UHPLC in interface with quadrupole time-of-flight mass spectrometry (Q TOFMS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Isorhamnetin inhibits adipogenesis by interfering with differentiation of adipose stem cells, by a mechanism involving stabilization of β-catenin and up-regulating the Wnt signaling pathway.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
LK9275450
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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