• USA Home
  • 402885 - p-Toluenesulfonic acid monohydrate

EMAIL THIS PAGE TO A FRIEND
402885 Sigma-Aldrich

p-Toluenesulfonic acid monohydrate

ACS reagent, ≥98.5%

  • CAS Number 6192-52-5

  • Linear Formula CH3C6H4SO3H · H2O

  • Molecular Weight 190.22

  •  Beilstein/REAXYS Number 3568023

  •  EC Number 203-180-0

  •  MDL number MFCD00142137

  •  PubChem Substance ID 24865132

  •  NACRES NA.21

Purchase

Properties

Related Categories Acids, Acids & Bases, Camostat Mesylate, Chemical Synthesis, Chemicals for the synthesis of candidate COVID-19 treatments,
Quality Level   200
grade   ACS reagent
vapor density   5.9 (vs air)
assay   ≥98.5%
clarity of soln   passes test
impurities   9.5-11.5% water
ign. residue   ≤0.1%
mp   103-106 °C (lit.)
solubility   H2O: 10g + 50 mL, clear, colorless
anion traces   sulfate (SO42-): ≤0.3%
cation traces   Fe: ≤0.01%
  Na: ≤0.002%
  heavy metals (as Pb): ≤0.001%
SMILES string   [H]O[H].Cc1ccc(cc1)S(O)(=O)=O
InChI   1S/C7H8O3S.H2O/c1-6-2-4-7(5-3-6)11(8,9)10;/h2-5H,1H3,(H,8,9,10);1H2
InChI key   KJIFKLIQANRMOU-UHFFFAOYSA-N

Description

General description

p-Toluenesulfonic acid monohydrate, an oxonium salt, is an inexpensive and easy to handle organic catalyst used in organic synthesis. The study of its crystalline structure shows that it is monoclinic with P21/c space group. Its solubility in aqueous sulfuric acid solutions has been studied.

Application

p-Toluenesulfonic acid monohydrate (p-TsOH·H2O) may be used as a catalyst in the synthesis of the following:
• Unsymmetrical benzils.
• Highly substituted piperidines.
• 1,3,5-Trisubstituted benzenes by trimerization of alkynes.
• Triazoloquinazolinone and benzimidazoquinazolinone derivatives.
• 1,3,5-Trisubstituted pyrazoles derivatives.
• Selenated ketene dithioacetals.

Packaging

100, 500 g in poly bottle

5 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 2585PSN2 8 / PGIII
WGK Germany 
WGK 1

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Related Content

Chemical Synthesis

Browse our portfolio for organic and inorganic chemicals for chemical synthesis, medicinal chemistry, and many other applications.
Keywords: Medicinal chemistry

Molarity Calculator & Normality Calculator for Acids & Bases

The molarity calculator tool provides lab-ready directions describing how to prepare an acid or base solution of specified Molarity (M) or Normality (N) from a concentrated acid or base solution. To ...

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?