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402923 Sigma-Aldrich

Chloroacetic acid

ACS reagent, ≥99.0%

Synonym: Monochloroacetic acid

  • CAS Number 79-11-8

  • Linear Formula ClCH2COOH

  • Molecular Weight 94.50

  •  Beilstein/REAXYS Number 605438

  •  EC Number 201-178-4

  •  MDL number MFCD00002683

  •  PubChem Substance ID 24865140

  •  NACRES NA.21

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Properties

Related Categories Acids, Acids & Bases, Chemical Synthesis, Organic Acids, Synthetic Reagents More...
Quality Level   200
grade   ACS reagent
vapor density   3.26 (vs air)
vapor pressure   0.75 mmHg ( 20 °C)
assay   ≥99.0%
impurities   ≤0.01% Carbonyl compounds (as acetone)
  ≤0.01% Carbonyl compunds (other than acetone)
  ≤0.01% insolubles
ign. residue   <0.02%
bp   189 °C (lit.)
mp   60-63 °C (lit.)
solubility   water: soluble 3170 g/L at 10 °C
anion traces   chloride (Cl-): ≤0.01%
  sulfate (SO42-): ≤0.02%
cation traces   Fe: ≤0.002%
  heavy metals (as Pb): ≤0.001%
SMILES string   OC(=O)CCl
InChI   1S/C2H3ClO2/c3-1-2(4)5/h1H2,(H,4,5)
InChI key   FOCAUTSVDIKZOP-UHFFFAOYSA-N

Description

General description

Chloroacetic acid (CAA, monochloroacetic acid, MCAA) is a halogenated aliphatic carboxylic acid generally used as herbicide and preservative. Its mutagenic effects have been studied in Rattus norvegicus. The rate of degradation of MCA by photocatalysis using TiO2 at pH3 is reported to be enhanced under the influence of ozone. CAA is an irritant that hydrolyzes proteins resulting in degradation of the cells. This property has been applied in treating plantar warts.

Application

Chloroacetic acid may be used to synthesize the following:
• Thiocarbamoylthioacetic acid derivatives.
• 4-Thiazolone derivatives.
• Triazinothiazolone derivatives.
• Water soluble carboxymethyl chitosan.

Packaging

100, 500 g in poly bottle

2 kg in poly bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Respiratory system
RIDADR 
UN 1751 8(6.1) / PGII
WGK Germany 
WGK 3
RTECS 
AF8575000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
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References

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