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41019 Supelco

Melting point standard 235-237°C

analytical standard

Synonym: 1,3,7-Trimethylxanthine, Caffeine

  • CAS Number 58-08-2

  • Empirical Formula (Hill Notation) C8H10N4O2

  • Molecular Weight 194.19

  •  Beilstein Registry Number 17705

  •  EC Number 200-362-1

  •  MDL number MFCD00005758

  •  PubChem Substance ID 329756046

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Melting Point Standards, Physical Properties Standards
grade   analytical standard
InChI Key   RYYVLZVUVIJVGH-UHFFFAOYSA-N
form   neat
shelf life   limited shelf life, expiry date on the label
mp   234-236.5 °C (lit.)
  235-237 °C (±0.3°C)
Featured Industry   Cosmetics, Personal Care, and Cleaning Products
Flavors and Fragrances
Food and Beverages
format   neat

Description

Biochem/physiol Actions

A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
EV6475000

Documents

Certificate of Analysis


Same Products - New Packaging
Protocols & Articles

Articles

GC Analysis of Basic Drugs on Equity®-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on Equity®-5
Keywords: Chromatography, Gas chromatography, Purification

GC Analysis of Basic Drugs on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents GC Analysis of Basic Drugs on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

HPLC Analysis of Acetaminophen, Caffeine, Chlorpheniramine, Ibuprofen, Naproxen, Phenylephrine, and Pseudoephedrine on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Acetaminophen, Caffeine, Chlorpheniramine, Ibuprofen, Naproxen, Phenylephrine, and Pseudoephedrine on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical, Separation

HPLC Analysis of Antihypertensive and Diuretic Drugs on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antihypertensive and Diuretic Drugs on Discovery® RP-Amide C16
Keywords: Antihypertensives, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Beverage Additives in Diet Cola on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Beverage Additives in Diet Cola on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Separation

HPLC Analysis of Beverage Additives in Diet Cola on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Beverage Additives in Diet Cola on Ascentis® Express RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Separation

HPLC Analysis of Bronchodilators Theophylline and Other Caffeine Metabolites in Serum on Discovery® RP-AmideC16 after SPE using Discovery® DSC-18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bronchodilators Theophylline and Other Caffeine Metabolites in Serum on Discovery® RP-AmideC16 after SPE using Discovery® DSC-18
Keywords: Calorimetry, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Sample preparations, Solid phase extractions

HPLC Analysis of Caffeine and Taurine on Ascentis® Express HILIC Column using Evaporative Light Scattering Detection (ELSD)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Caffeine and Taurine on Ascentis® Express HILIC Column using Evaporative Light Scattering Detection (ELSD)
Keywords: Chromatography, High performance liquid chromatography, Normal-phase chromatography, Separation, Vitamins

HPLC Analysis of Caffeine and Taurine on Ascentis® Express HILIC Column using Evaporative Light Scattering Detection (ELSD, Fast Analysis)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Caffeine and Taurine on Ascentis® Express HILIC Column using Evaporative Light Scattering Detection (ELSD, Fast Analysis)
Keywords: Chromatography, High performance liquid chromatography, Normal-phase chromatography, Separation, Vitamins

HPLC Analysis of Pain Relievers on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Pain Relievers on Ascentis® Express C18
Keywords: Analgesics, Chromatography, Clinical, High performance liquid chromatography

HPLC Analysis of an Energy Drink on Ascentis® Express HILIC (UV Detection)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of an Energy Drink on Ascentis® Express HILIC (UV Detection)
Keywords: Chromatography, Detection methods, High performance liquid chromatography, Separation, Vitamins

TLC Analysis Report of Analgesics on HPTLC Silica Gel 60 RP-18 WF254s (analyte set 2)

From our library of Articles, Sigma-Aldrich presents TLC Analysis Report of Analgesics on HPTLC Silica Gel 60 RP-18 WF254s (analyte set 2)
Keywords: Chromatography, Pharmaceutical, Thin layer chromatography

TLC Analysis of Analgesics on HPTLC Silica Gel 60 RP-18 WF254s (analyte set 2)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Analgesics on HPTLC Silica Gel 60 RP-18 WF254s (analyte set 2)
Keywords: Chromatography, Pharmaceutical, Thin layer chromatography

TLC Analysis of Expectorants on HPTLC Silica Gel 60 RP-18 WF254s

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Expectorants on HPTLC Silica Gel 60 RP-18 WF254s
Keywords: Chromatography, Pharmaceutical, Thin layer chromatography

Peer-Reviewed Papers
15

References

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