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439126 Sigma-Aldrich

Acetone

for HPLC, ≥99.9%

  • CAS Number 67-64-1

  • Linear Formula CH3COCH3

  • Molecular Weight 58.08

  •  Beilstein Registry Number 635680

  •  EC Number 200-662-2

  •  MDL number MFCD00008765

  •  PubChem Substance ID 57650186

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Properties

Related Categories Acetone, Analytical Reagents, Analytical/Chromatography, Chromatography Reagents & Solvents, HPLC,
grade   for HPLC
vapor density   2 (vs air)
vapor pressure   184 mmHg ( 20 °C)
InChI Key   CSCPPACGZOOCGX-UHFFFAOYSA-N
assay   ≥99.9%
expl. lim.   13.2 %
impurities   ≤0.5% (water)
evapn. residue   <0.0002%
color   colorless
refractive index   n20/D 1.359(lit.)
bp   56 °C/760 mmHg(lit.)
mp   −94 °C (lit.)
solubility   water: miscible
density   0.791 g/mL at 25 °C(lit.)
λ   H2O reference
UV absorption   λ: 330 nm Amax: 1.00
  λ: 340 nm Amax: 0.10
  λ: 350 nm Amax: 0.02
  λ: 400 nm Amax: 0.01
suitability   suitable (pesticide analysis)

Description

Packaging

18 L in VerSA-Flow™

2×10 L in Nowpak™

20 L in Nowpak™

4, 4×4 L in PVC-coated bottle

200 L-P2 in Pure-Pac™ 2

50 L in composite drum

Application

Acetone was used in the affinity purification of modified proteins using streptavidin beads for the mass spectrometric (MS) identification of poly(ADP-ribose) polymerases (PARP) substrate proteins.
It may be used in the following studies:
• NMR spectroscopic evaluation of glucose metabolism in biological samples (blood).
• Preparation of 13wt% amorphous poly (lactic acid) (PLA) solution, which was required for the preparation of electrospun PLA membranes.
• As a precursor for the synthesis of methyl isobutyl ketone (MIBK) in the presence of sulfonated graphene oxide-Pd/cordierite catalyst.
• Synthesis of (4-hydroxymethyl-2,2-dimethyl-1,3-dioxolane), a solketal from glycerol using supercritical fluids (SCF) technology.
It may be used in the synthesis of the following acetone hydrazones:
• 1-isopropylidene-2-methylhydrazine
• 1-isopropylidene-2-hydroxyethylhydrazine
• 1-isopropylidene-2-formylhydrazine

Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

General description

Acetone is a ketone. Mixtures of TiO2 (P25) with rare earth oxides (La2O3 or Y2O3) calcined at 700°C or 650°C has been reported to efficiently photocatalyze the oxidation of acetone. Its aldol condensation in vapor-phase has been investigated over MgO promoted with alkali (Li, Na, K and Cs) or alkaline earth (Ca, Sr and Ba) metal ions. It undergoes Aldol condensation in the presence of Mg-Al layered double hydroxides (LDH) as catalysts and Cl- and/or CO32- as compensating anions to afford diacetone alcohol and mesityl oxide. Enantioselective Aldol condensation of acetone with various isatins in the presence of dipeptides (catalyst) has been described.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Repeated exposure may cause skin dryness or cracking.
RIDADR 
UN1090 - class 3 - PG 2 - Acetone
WGK Germany 
1
RTECS 
AL3150000
Flash Point(F) 
1.4 °F
Flash Point(C) 
-17 °C

Documents

Certificate of Analysis

Certificate of Origin


Same Products - New Packaging
Protocols & Articles

Articles

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Related Content

Pressure-Temperature Nomograph Interactive Tool

The Pressure-Temperature Nomograph tool is an application of the Clausius-Clapeyron Equation, which assumes the heat of vaporization is a constant over a pressure range. Antoine´s Equation gets aroun...
Keywords: Evaporation, Vaporization

Properties of Solvents Table

a. Gant, R., LC/GC 10 (7), 515 (1992) 1. At 20 °C 2. At 20 °C +/- 5 °C relative to water at 4 °C 3. At 10 mmHg pressure 4. At l=589.32 nm
Keywords: Gas chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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