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Sulfamethazine

VETRANAL, analytical standard

Synonym: 4,6-Dimethylsulfadiazine, 4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide, Sulfadimethyldiazine, Sulfadimidine

  • CAS Number 57-68-1

  • Empirical Formula (Hill Notation) C12H14N4O2S

  • Molecular Weight 278.33

  •  Beilstein/REAXYS Number 261304

  •  EC Number 200-346-4

  •  MDL number MFCD00006066

  •  PubChem Substance ID 329757245

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Properties

Related Categories 1694 Pharmaceuticals & Personal Care Products, Additional Standards, Analytical Standards, Analytical/Chromatography, Antibacterial,
grade   analytical standard
InChI Key   ASWVTGNCAZCNNR-UHFFFAOYSA-N
product line   VETRANAL
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Agency/Method   EPA 1694
Featured Industry   Environmental
Pharmaceutical (small molecule)
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
format   neat

Description

General description

Chemical structure: sulfonamide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

An antimicrobial sulfur drug. Induces CYP3A4 expression and acetylated by N-acetyltransferase. Exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11.

Legal Information

VETRANAL is a trademark of Sigma-Aldrich Chemie GmbH

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
WO9275000

Documents

Certificate of Analysis

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Protocols & Articles

Articles

HPLC Analysis of Sulfa Drugs on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Sulfa Drugs on Discovery® C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

Related Products

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