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47673 Sigma-Aldrich

Formaldehyde solution

tested according to Ph. Eur.

Synonym: Formaldehydi solutio 35 per centum, Formalin

  • CAS Number 50-00-0

  • Linear Formula HCHO

  • Molecular Weight 30.03

  •  Beilstein/REAXYS Number 1209228

  •  MDL number MFCD00003274

  •  PubChem Substance ID 329757334

  •  NACRES NA.25

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Properties

Agency/Method   tested according to Ph. Eur.
Quality Level   200
vapor density   1.03 (vs air)
vapor pressure   52 mmHg ( 37 °C)
autoignition temp.   572 °F
contains   9.0-15.0 % (v/v) methanol as stabilizer
concentration   25-50%
solubility   water: soluble
density   1.09 g/mL at 25 °C (lit.)
suitability   suitable for manufacturing use (Laboratory chemicals)
storage temp.   room temp
SMILES string   [H]C([H])=O
InChI   1S/CH2O/c1-2/h1H2
InChI key   WSFSSNUMVMOOMR-UHFFFAOYSA-N

Description

Application

Formaldehyde solution has been used to fix labeled cells during flow cytometry.

Biochem/physiol Actions

Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.

Caution

may become turbid on storage

Safety & Documentation

Safety Information

Signal word 
Danger
Target organs 
Respiratory system
RIDADR 
UN 2209 8 / PGIII
WGK Germany 
WGK 3
Flash Point(F) 
133.0 °F - closed cup
Flash Point(C) 
56.11 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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