48912-U Sigma-Aldrich

ProClin 300

pkg of 50 mL

  •  NACRES NA.21



Related Categories Biochemicals and Reagents, Biocides, Biocides for In Vitro Diagnostics (IVD) Applications, ProClin 300, ProClin Preservatives More...
contains   Alkyl Carboxylate
composition   CMIT/MIT, 3%
packaging   pkg of 50 mL
matrix   Modified glycol
operating pH range   2.5 - 8.5



ProClin biocides are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin toxicity prevent microorganisms from developing high levels of resistance, making ProClin highly efficient even over extended storage periods of your IVD components.

For use in biological diagnostic assays and IVDs only


For additional technical details on ProClin, including key features and mechanism of action, please visit

Legal Information

ProClin is a trademark of The Dow Chemical Company or an affiliated company of Dow

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
UN 3265 8/PG 2
WGK Germany 
Flash Point(F) 
151 °F
Flash Point(C) 
66 °C


Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is the concentration of active ingredients in ProClin 300?
ProClin 300 contains a total of 3% active ingredient.
What is the matrix of the ProClin 300?
ProClin 300 is a viscous solution containing 93-95 % Modified glycol and 2-3 % Alkyl carboxylate.
When would I choose to use ProClin 300?
ProClin 300 is best used with production runs of standards, controls, and large volume buffers and solutions.The product is quite viscous and difficult to work with when trying to measure small volumes.
What are the active ingredients in ProClin 300?
ProClin 300 contains two active ingredients: 5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT, CAS RN 26172-55-4) and 2-Methyl-4-isothiazolin-3-one (MIT, CAS RN 2682-20-4).
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the density of ProClin 300?
The density of ProClin 300 is reported as 8.59 pounds per gallon. The specific gravity at 22°C is reported as 1.03 g/mL.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions
Protocols & Articles

Related Content

Coronavirus COVID-19 (SARS-CoV-2) Detection, Characterization & Vaccine Production

As a global life science tools and equipment supplier, we are here to help in the response to COVID-19. From supplying raw materials and research products for detection and characterization to produc...
Keywords: PAGE

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?