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Carnosol

analytical standard

Synonym: Picrosalvin

  • CAS Number 5957-80-2

  • Empirical Formula (Hill Notation) C20H26O4

  • Molecular Weight 330.42

  •  MDL number MFCD02752467

  •  PubChem Substance ID 329757507

  •  NACRES NA.24

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Properties

Related Categories A - D, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography, Isoprenoids,
Quality Level   100
biological source   Rosemarinus officinalis L. leaves
grade   analytical standard
InChI Key   XUSYGBPHQBWGAD-PJSUUKDQSA-N
assay   ≥98.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Food and Beverages
format   neat
storage temp.   −20°C

Description

General description

Carnosol is a naturally occurring phyto polyphenolor phenolic diterpene, found in rosemary, which can show a broad spectrum of applications as a an antioxidant, anticancer agent and anti-inflammatory agent.

Carnosol is one of the phenolic antioxidants present in extracts of the herb rosemary (Rosmarinus officinalis). Carnosol inhibits the formation of tumors derived using irritants such as TPA and DMBA in murine models of carcinogenesis.The effective dose reported is 1-10 μM topically or 6 μg/ml when added to supernatants of cultured cells.Addition of rosemary extracts to the diet as a 1% supplement by weight was also found to decrease the frequency of DMBA-DNA adducts.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

A phenolic diterpene with antioxidant and anticarcinogenic activities.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Phenolics from Rosemary on Ascentis® Express C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Phenolics from Rosemary on Ascentis® Express C8
Keywords: Chromatography, High performance liquid chromatography, Separation, Vitamins

Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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