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556416 Sigma-Aldrich

New Methylene Blue N

Dye content ~70 %

Synonym: Basic Blue 24, Methylene Blue N

  • CAS Number 1934-16-3

  • Empirical Formula (Hill Notation) C18H22ClN3S

  • Molecular Weight 347.91

  •  Colour Index Number 52030

  •  EC Number 217-696-9

  •  MDL number MFCD00135878

  •  PubChem Substance ID 24879556

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Properties

InChI Key   NZYCYASKVWSANA-UHFFFAOYSA-M
composition   Dye content, ~70%
mp   190 °C (dec.) (lit.)
absorption   λmax 590 nm
  λmax 632 nm (2nd)

Description

Features and Benefits

Solvent soluble cationic thiazine dye

Packaging

1, 10 g in glass bottle

Application

New methylene blue N has been used as a photosensitizer for the photodynamic inactivation of Candida albicans.

Biochem/physiol Actions

New methylene blue N can bind, neutralize and crosslink with RNA. This causes co-precipitation of ribosomal and residual RNA with the mitochondria and ferritin masses. These events make the living young erythrocytes as microscopically visible, dark-blue clusters and filaments, referred to as reticulum. New Methylene Blue N helps in counting of reticulocytes (erythrocytes containing RNA).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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