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60063 Sigma-Aldrich

Potassium antimonyl tartrate trihydrate

purum p.a., 99.0-103% (RT)

Synonym: Antimony potassium tartrate trihydrate, Tartar emetic

  • CAS Number 28300-74-5

  • Empirical Formula (Hill Notation) C8H4K2O12Sb2 · 3H2O

  • Molecular Weight 667.87

  •  EC Number 234-293-3

  •  MDL number MFCD00167056

  •  PubChem Substance ID 57651716

  •  NACRES NA.21

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Properties

Related Categories Essential Chemicals, Potassium Salts, Research Essentials, Salts
Quality Level   200
grade   purum p.a.
assay   99.0-103% (RT)
loss   ≤2.7% loss on drying
mp   ≥300 °C (lit.)
anion traces   chloride (Cl-): ≤100 mg/kg
  sulfate (SO42-): ≤500 mg/kg
cation traces   Ca: ≤50 mg/kg
  Cd: ≤50 mg/kg
  Co: ≤50 mg/kg
  Cu: ≤50 mg/kg
  Fe: ≤50 mg/kg
  Na: ≤500 mg/kg
  Ni: ≤50 mg/kg
  Pb: ≤50 mg/kg
  Zn: ≤50 mg/kg
SMILES string   O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
InChI   1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
InChI key   WBTCZEPSIIFINA-UHFFFAOYSA-J

Description

General description

Potassium antimonyl tartrate trihydrate is a trivalent antimony compound. It has been reported to be a leishmanicidal compound and exhibits more toxic action than pentavalent antimony (Pentostam) against Leishmania species. Three-dimensional X-ray and white radiation neutron diffraction methods have been reported to investigate the crystal structure of its optically active form (dipotassium di-μ-d-tartrato (4)-bis(antimonate(III)) trihydrate). Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.

Application

Potassium antimonyl tartrate trihydrate may be used as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 1551 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
CC6825000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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