• USA Home
  • 62929 - L-Lysine monohydrochloride

EMAIL THIS PAGE TO A FRIEND
62929 Sigma-Aldrich

L-Lysine monohydrochloride

BioUltra, ≥99.5% (AT)

Synonym: (S)-2,6-Diaminohexanoic acid monohydrochloride

  • CAS Number 657-27-2

  • Linear Formula H2N(CH2)4CH(NH2)CO2H·HCl

  • Molecular Weight 182.65

  •  Beilstein/REAXYS Number 3563889

  •  EC Number 211-519-9

  •  MDL number MFCD00064564

  •  PubChem Substance ID 329759756

  •  NACRES NA.26

Purchase

Properties

Related Categories Amino Acids, BioUltra, Biochemicals and Reagents More...
InChI Key   BVHLGVCQOALMSV-JEDNCBNOSA-N
product line   BioUltra
assay   ≥99.5% (AT)
optical activity   [α]20/D +20.5±0.5°, c = 5% in 5 M HCl
impurities   insoluble matter, passes filter test
  ≤0.3% foreign amino acids
ign. residue   ≤0.1% (as SO4)
loss   ≤0.5% loss on drying, 20 °C (HV)
pH   5.0-6.0 (25 °C, 0.5 M in H2O)
mp   263 °C (dec.) (lit.)
solubility   H2O: 0.5 M at 20 °C, clear, colorless
anion traces   sulfate (SO42-): ≤100 mg/kg
cation traces   Al: ≤5 mg/kg
  As: ≤0.1 mg/kg
  Ba: ≤5 mg/kg
  Bi: ≤5 mg/kg
  Ca: ≤10 mg/kg
  Cd: ≤5 mg/kg
  Co: ≤5 mg/kg
  Cr: ≤5 mg/kg
  Cu: ≤5 mg/kg
  Fe: ≤5 mg/kg
  K: ≤50 mg/kg
  Li: ≤5 mg/kg
  Mg: ≤5 mg/kg
  Mn: ≤5 mg/kg
  Mo: ≤5 mg/kg
  NH4+: ≤100 mg/kg
  Na: ≤50 mg/kg
  Ni: ≤5 mg/kg
  Pb: ≤5 mg/kg
  Sr: ≤5 mg/kg
  Zn: ≤5 mg/kg
λ   0.5 M in H2O
UV absorption   λ: 260 nm Amax: 0.1
  λ: 280 nm Amax: 0.1

Description

General description

L-Lysine is an essential amino acid, not generated by the body, instead must be supplemented through food.

Application

L-Lysine monohydrochloride has been used:
• to study its effect on mRNA decay and destruction using mammalian cells
• to determine its effec on aTC1-6 cell proliferation
• to study the dynamics of the phosphoproteome upon amino acid supplement removal in the growth medium

Biochem/physiol Actions

L-Lysine is associated with a number of biochemical reactions such as acetylation, O-linked glycosylation, ubiquitination and protein methylation. Lysine participates in the regulation of NO (nitric oxide) synthesis. It possesses antiviral activity, therefore it is used in the treatment of Herpes simplex. L-Lysine is believed to prevent osteoporosis of bones, which is a characteristic of vascular calcification. Glutaric aciduria type I and pyridoxine-dependent epilepsy occurs due to lack of L-lysine catabolic pathway. Hydroxylysine is a component of collagen

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
OL5650000

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Related Content

Amino Acids Reference Charts

Amino acids are the compounds or building blocks that make up peptides and proteins. Each amino acid is structured from an amino group and a carboxyl group bound to a tetrahedral carbon. This carbon ...
Keywords: Building blocks, Gene expression, Mass spectrometry

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?