• USA Home
  • 64682 - Pyrroloquinoline quinone

EMAIL THIS PAGE TO A FRIEND
64682 Sigma-Aldrich

Pyrroloquinoline quinone

≥97.0% (HPLC)

Synonym: 4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, Methoxatin, PQQ

  • CAS Number 72909-34-3

  • Empirical Formula (Hill Notation) C14H6N2O8

  • Molecular Weight 330.21

  •  Beilstein/REAXYS Number 3596812

  •  MDL number MFCD00043125

  •  PubChem Substance ID 329759991

Purchase

Properties

Related Categories Biochemicals and Reagents, Cofactors, Enzymes, Inhibitors, and Substrates, Oxidation-Reduction
assay   ≥97.0% (HPLC)
form   powder
impurities   ≤15% water
color   red to dark red
storage temp.   2-8°C
SMILES string   OC(=O)c1cc(C(O)=O)c-2c(n1)C(=O)C(=O)c3cc([nH]c-23)C(O)=O
InChI   1S/C14H6N2O8/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18/h1-2,15H,(H,19,20)(H,21,22)(H,23,24)
InChI key   MMXZSJMASHPLLR-UHFFFAOYSA-N

Description

General description

Novel o-quinone coenzyme found in bacterial dehydrogenases and oxidases.

Biochem/physiol Actions

PQQ is present in nanomolar quantities in most foods and in most animal tissuse. It promotes growth, mitochondrial function, and development in vivo and stimulates cell proliferation and viability in culture. It is a potent antioxidant that scavenges superoxide and peroxinitrite. It is neuroprotectant against 6-hydroxydopamine-induced and hypoxia/ischemia-induced neurotoxicity. PQQ conjugates to α-synuclein in vitro, inhibiting the formation of amyloid fibrils.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

replaced by

Product #

Description

Add to Cart

D7783 Pyrroloquinoline quinone, ≥95.0% (HPLC)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?