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675415 Sigma-Aldrich

Acetonitrile

HPLC Plus, ≥99.9%, poly-coated bottles

Synonym: ACN, Methyl cyanide

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Properties

Related Categories Acetonitrile and Acetonitrile Solutions, Solvent by Type, Solvents More...
grade   HPLC Plus
vapor density   1.41 (vs air)
vapor pressure   72.8 mmHg ( 20 °C)
InChI Key   WEVYAHXRMPXWCK-UHFFFAOYSA-N
assay   ≥99.9%
form   liquid
autoignition temp.   525 °F
  973 °F
expl. lim.   16 %
impurities   ≤0.01% water
evapn. residue   ≤0.0002%
color   colorless
refractive index   n20/D 1.344 (lit.)
bp   81-82 °C(lit.)
mp   −48 °C (lit.)
solubility   water: soluble
density   0.786 g/mL at 25 °C (lit.)
UV absorption   λ: 195 nm Amax: ≤0.10
  λ: 200 nm Amax: ≤0.02
  λ: 228 nm Amax: ≤0.005

Description

General description

Acetonitrile (MeCN), an aliphatic nitrile, is a colorless liquid with a pleasant odor. It is widely used as a solvent and intermediate in organic syntheses. It is transparent to UV-visible light making it highly applicable in spectrophotometric and fluorimetric techniques. As MeCN has low viscosity, high elution strength and is highly miscible in water, it is utilized as a mobile phase component in many chromatographic techniques. Its infrared spectrum has been recorded. Synthesis of alkyl hydroperoxides in MeCN by alkane oxidation with hydrogen peroxide in the presence of iron complexes has been studied. The hydrogenation of MeCN to form ethylamine using Co–B amorphous alloy catalyst has been investigated.

Packaging

4, 4×4 L in PVC-coated bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1648 3 / PGII
WGK Germany 
2
RTECS 
AL7700000
Flash Point(F) 
35.6 °F
Flash Point(C) 
2 °C

Documents

Certificate of Analysis

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Certificate of Origin

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PTFE Millex filter
Protocols & Articles

Articles

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Keywords: Adsorption, Chromatography, Gas chromatography, Mass spectrometry, Pesticides, Sample preparations, Solid phase extractions

GC Analysis of Pesticide Residues in Hops on SLB®-5ms after QuEChERS Extraction then QuEChERS Cleanup using Supel™ QuE Verde

From our library of Articles, Sigma-Aldrich presents GC Analysis of Pesticide Residues in Hops on SLB®-5ms after QuEChERS Extraction then QuEChERS Cleanup using Supel™ QuE Verde
Keywords: Adsorption, Chromatography, Gas chromatography, High performance liquid chromatography, Mass spectrometry, Pesticides, Sample preparations, Solid phase extractions

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

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Pressure-Temperature Nomograph Interactive Tool

Use the interactive controls above to simplify calculations and improve the efficiency of your distillation or evaporation requirements.
Keywords: Evaporation, Vaporization

Properties of Solvents Table

The table below presents the physical characteristics of common solvents. Easily reference or compare solvent properties like boiling point, density, and refractive index all from one list.
Keywords: Gas chromatography, Green chemistry, High performance liquid chromatography, Melting, Solvents

Peer-Reviewed Papers
15

References

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