• USA Home
  • 675970 - Cyclopentyl methyl ether

EMAIL THIS PAGE TO A FRIEND
675970 Sigma-Aldrich

Cyclopentyl methyl ether

Green Alternative

contains 50 ppm BHT as inhibitor, anhydrous, ≥99.9%

Synonym: CPME

  • CAS Number 5614-37-9

  • Empirical Formula (Hill Notation) C6H12O

  • Molecular Weight 100.16

  •  MDL number MFCD08276401

  •  PubChem Substance ID 57652096

  •  NACRES NA.21

Purchase

Properties

Related Categories Anhydrous Solvents, Greener Solvent Alternatives, Greener Substitutes, Solvent by Type, Solvent Bottles,
Quality Level   100
grade   anhydrous
assay   ≥99.9%
form   liquid
contains   50 ppm BHT as inhibitor
greener alternative product characteristics   Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.
impurities   ≤0.0050% H2O
  ≤0.0050% water
water
  ≤50 ppm H2O2
evapn. residue   <0.003%
bp   106 °C/760 mmHg
mp   -140 °C (lit.)
density   0.86 g/mL at 25 °C
greener alternative category   Aligned
SMILES string   COC1CCCC1
InChI   1S/C6H12O/c1-7-6-4-2-3-5-6/h6H,2-5H2,1H3
InChI key   SKTCDJAMAYNROS-UHFFFAOYSA-N

Description

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. Cyclopentyl methyl ether (CPME) is a greener alternative to other ethereal solvents such as tetrahydrofuran (THF), 2-methyl tetrahydrofuran (2-MeTHF), dioxane (carcinogenic), tert-Butyl methyl ether (MTBE), and 1,2-dimethoxyethane (DME) and thus has been enhanced for "Safer Solvents and Auxiliaries". Click here for more information.

Application

• Cyclopentyl methyl ether (CPME) is an alternative to ether solvents such as THF, diethyl ether, and MTBE with a higher resistance to peroxide formation.
• The more environmentally conservative CPME solvent replaces hazardous solvents in order to achieve sustainability and reduce environmental and operational costs.
• CPME offers considerable potential and advantage as a direct replacement for CH2Cl2 in binary eluents using MeOH as the modifier with MeOH–DMC and i-PrOH–EtOAc.

Green Alternative to THF, tert-Butyl methyl ether (MTBE), 1,4 Dioxane and other ether solvents

The toxicological assessment of cyclopentyl methyl ether (CPME) as a green solvent.

Packaging

1, 2 L in Sure/Seal™

100, 12×100 mL in Sure/Seal™

Features and Benefits

Greener alternative for THF, Diethyl ether, and MTBE

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3271 3 / PGII
WGK Germany 
WGK 3
Flash Point(F) 
30.2 °F - closed cup
Flash Point(C) 
-1 °C - closed cup

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions
Protocols & Articles

Articles

Anhydrous Solvents for Coupling Reactions

Due to the sensitivity to air and moisture, coupling reactions often require relatively low air and water conditions to initiate the reaction. Therefore, the use of anhydrous solvents is highly recom...
Keywords: Coupling reactions, Cross couplings, Negishi Coupling, Solvents

Anhydrous Solvents for Organic and Organometallic Chemistry

Many well-known reactions require water-free conditions to initiate or complete the reaction. Failure to include anhydrous solvents can result in low product yield or reaction failure. As the market ...
Keywords: Acylations, Alkylations, Electrophilic aromatic substitution, Formylations, Grignard Reaction, Solvents, Substitutions, Vilsmeier-Haack reaction

Pressure-Temperature Calculator for Solvents

*Calculations provide estimated results based on Antoine's Coefficients and their associated temperature range values. Antoine's Coefficients were obtained from the National Institute of Standards an...

Stereospecific Cross-Coupling of Secondary Organotrifluoroborates: Potassium 1-(Benzyloxy)alkyltrifluoroborates

The synthesis of potassium trifluoro(N-methylheteroaryl)borates and their use in cross-coupling reactions with various aryl and heteroaryl halides to construct N-methyl heteroaryl-substituted aromati...
Keywords: Chromatography, Column chromatography, Coupling reactions, Cross couplings

Suzuki-Miyaura Cross-Coupling of Potassium Trifluoro(N-methylheteroaryl)borates with Aryl and Heteroaryl Halides

A new bulky biarylphosphine ligand (L8) has been developed that allows the Pd-catalyzed C-O cross-coupling of a wide range of aryl halides and phenols under milder conditions than previously possible...
Keywords: Catalysis, Chromatography, Cross couplings, Flash chromatography, Ligands

Related Content

Greener Alternatives Four Categories

A new icon has been added to identify our Greener alternative products. Products with this icon fulfill one of the four criteria.
Keywords: Alternative energy, Environmental, Green chemistry, PAGE, Solvents, Substitutions

Lab Chemicals

From our library of Related Content, Sigma-Aldrich presents Lab Chemicals
Keywords: Gas chromatography, Infrared spectroscopy, Sublimation, Thin layer chromatography

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?