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72210 Sigma-Aldrich

Neutral Red

for microscopy (Bact., Bot., Fl., Hist., Vit.), indicator (pH 6.8-8.0)

Synonym: 3-Amino-7-dimethylamino-2-methylphenazine hydrochloride, Basic Red 5, Toluylene red

  • CAS Number 553-24-2

  • Empirical Formula (Hill Notation) C15H17ClN4

  • Molecular Weight 288.78

  •  Colour Index Number 50040

  •  Beilstein/REAXYS Number 3918740

  •  EC Number 209-035-8

  •  MDL number MFCD00012651

  •  PubChem Substance ID 329763896

  •  NACRES MA.02

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Properties

Related Categories Analytical Reagents, Analytical/Chromatography, Indicators, Microscopy Reagents, Redox Indicators,
Quality Level   100
grade   for microscopy (Bact., Bot., Fl., Hist., Vit.)
  indicator (pH 6.8-8.0)
form   powder or crystals
application(s)   hematology: suitable
  histology: suitable
  titration: suitable
pH range   6.8 - 8.0, red to yellow
mp   290 °C (dec.) (lit.)
solubility   water: 0.01 g/10 mL
εmax   ≥800 at 535-545 nm
Featured Industry   Diagnostic Assay Manufacturing
storage temp.   room temp
SMILES string   Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1
InChI   1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H
InChI key   PGSADBUBUOPOJS-UHFFFAOYSA-N

Description

General description

Neutral red is a vital dye widely used as a cellular pH indicator and is selective for shifts in pH. It is highly lipophilic in nature. It favours membrane potential dependent fluorescence that attributes to changes in hydrophobicity.

Application

Neutral red has been used to stain mouse mammary glands.

Useful as an indicator for preparing neutral red paper, and as a biological stain.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
SG1400000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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