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Iohexol

analytical standard

Synonym: 5-[N-(2,3-Dihydroxypropyl)acetamido]-2,4,6-triiodo-N,N′-bis(2,3-dihydroxypropyl)isophthalamide

  • CAS Number 66108-95-0

  • Empirical Formula (Hill Notation) C19H26I3N3O9

  • Molecular Weight 821.14

  •  Beilstein/REAXYS Number 2406632

  •  EC Number 266-164-2

  •  MDL number MFCD00077732

  •  PubChem Substance ID 329765500

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Properties

Related Categories Additional Drugs, Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography,
grade   analytical standard
InChI Key   NTHXOOBQLCIOLC-UHFFFAOYSA-N
assay   ≥95.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
impurities   ≤6.0% water
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker to determine the glomerular filtration rate (GFR) which measures the level of kidney function. It finds applications in angiographic and urography procedures.

Application

Iohexol may be used as an internal standard for the determination of iohexol in human plasma, serum and urine samples by HPLC-UV method. It may also be used as a model compound to analyze the applicability of iohexol for glomerular filtration rate (GFR) measurement by the plasma clearance of iohexol in investigating renal failure.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
CZ2205000

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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