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L-Leucine

certified reference material, TraceCERT®

Synonym: (S)-2-Amino-4-methylpentanoic acid

  • CAS Number 61-90-5

  • Linear Formula (CH3)2CHCH2CH(NH2)CO2H

  • Molecular Weight 131.17

  •  Beilstein/REAXYS Number 1721722

  •  EC Number 200-522-0

  •  MDL number MFCD00002617

  •  eCl@ss 32160406

  •  PubChem Substance ID 329767169

  •  E Number E641

  •  NACRES NA.24

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Properties

Related Categories A-L, Additional Standards, All Alphabetically Sorted, Amino Acid Standards, Amino Acid, Peptide & Protein Standards,
Quality Level   300
grade   certified reference material
  TraceCERT®
form   neat
analyte chemical class(es)   amino acids, peptides, proteins
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
color   white
mp   >300 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Flavors and Fragrances
Food and Beverages
Personal Care
format   neat
storage temp.   20-25°C
SMILES string   CC(C)C[C@H](N)C(O)=O
InChI   1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key   ROHFNLRQFUQHCH-YFKPBYRVSA-N

Description

General description

L-Leucine is an important and essential branched chain amino acid. It shows activity with the mechanistic target of rapamycin(mTOR) pathway, involved in the synthesis of proteins and satiety.

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034 (ISO Guide 34). This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

HPLC Analysis of Dansyl-Leucine Enantiomers on Astec® CHIROBIOTIC® R

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Dansyl-Leucine Enantiomers on Astec® CHIROBIOTIC® R
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Leucine Enantiomers on Astec® CHIROBIOTIC® T (25 °C)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Leucine Enantiomers on Astec® CHIROBIOTIC® T (25 °C)
Keywords: Chromatography, High performance liquid chromatography

Separation of Amino Acids on Cellulose (Set 2)

From our library of Articles, Sigma-Aldrich presents Separation of Amino Acids on Cellulose (Set 2)

Separation of amino acids on Cellulose TLC plates

a) 1-butanol/acetone/glacial acetic acid/water 35/35/7/23 (v/v) b) 1-butanol/acetone/glacial acetic acid/water 35/35/7/23 (v/v) + 1mL Ninhydrin solution Ninhydrin solution: 7g Ninhydrin in 100mL acet...
Keywords: Thin layer chromatography

TLC Analysis of Amino Acids on HPTLC Pre-coated Cellulose without Fluorescent Indicator

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Amino Acids on HPTLC Pre-coated Cellulose without Fluorescent Indicator
Keywords: Indicators, Thin layer chromatography

Related Content

Flavor and Fragrance Analysis

We offer quality product solutions in all three stages of analysis to help achieve fast, accurate results. Below, you can learn more about our workflow solutions for sample preparation, separation, d...
Keywords: Calorimetry, Chromatography, Environmental, Gas chromatography, Mass spectrometry, Pesticides, Sample preparations, Separation

Peer-Reviewed Papers
15

References

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