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Glycerol

analytical standard

Synonym: 1,2,3-Propanetriol, Glycerin

  • CAS Number 56-81-5

  • Linear Formula HOCH2CH(OH)CH2OH

  • Molecular Weight 92.09

  •  Beilstein/REAXYS Number 635685

  •  EC Number 200-289-5

  •  MDL number MFCD00004722

  •  PubChem Substance ID 329767462

  •  NACRES NA.24

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Properties

Related Categories A-L, Analytical Standards, Analytical/Chromatography, Chinese Food Contact Materials Regulation GB 9685 2016, Cosmetics & Perfumes,
Quality Level   100
grade   analytical standard
vapor density   3.1 (vs air)
vapor pressure   <1 mmHg ( 20 °C)
assay   ≥98.5% (GC)
form   neat
autoignition temp.   698 °F
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
impurities   ≤0.3% water
refractive index   n20/D 1.474 (lit.)
bp   182 °C/20 mmHg (lit.)
mp   20 °C (lit.)
density   1.25 g/mL (lit.)
Featured Industry   Cleaning Products
Cosmetics
Flavors and Fragrances
Food and Beverages
Personal Care
format   neat
SMILES string   OCC(O)CO
InChI   1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChI key   PEDCQBHIVMGVHV-UHFFFAOYSA-N

Description

General description

Glycerol is a simple polyol compound, which is obtained as a byproduct of soap and biodiesel industries.

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

Application

Glycerol has been used as
• a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
• a fuel during designing enzymatic biofuel cell.
• a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
• a matrix for fast atom bombardment MS.
• may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.

Glycerol may be used as a reference standard in the determination of glycerol in samples of beer using gas liquid chromatography (GLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.

Biochem/physiol Actions

Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
MA8050000
Flash Point(F) 
390.2 °F - Pensky-Martens closed cup
Flash Point(C) 
199 °C - Pensky-Martens closed cup
Protocols & Articles

Articles

ASTM D6584: GC Analysis of Glycerin Impurity in B100 Biodiesel on MET-Biodiesel

From our library of Articles, Sigma-Aldrich presents ASTM D6584: GC Analysis of Glycerin Impurity in B100 Biodiesel on MET-Biodiesel
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Glycols on Nukol™

From our library of Articles, Sigma-Aldrich presents GC Analysis of Glycols on Nukol™
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

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Flavor and Fragrance Analysis

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Peer-Reviewed Papers
15

References

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