77450 Supelco


for GC derivatization, LiChropur, ≥99.0%

Synonym: ω-Bromoacetophenone, Phenacyl bromide

  • CAS Number 70-11-1

  • Linear Formula C6H5COCH2Br

  • Molecular Weight 199.04

  •  Beilstein/REAXYS Number 606474

  •  EC Number 200-724-9

  •  MDL number MFCD00000195

  •  PubChem Substance ID 329767691



Related Categories Acylation Reagents, Analytical Reagents, Analytical/Chromatography, Derivatization Reagents, Derivatization Reagents GC,
grade   for GC derivatization
assay   ≥99.0% (GC)
quality   LiChropur
bp   135 °C/18 mmHg(lit.)
mp   48-51 °C (lit.)
  49-50 °C
storage temp.   2-8°C


General description

2-Bromoacetophenone is a commonly used derivatization agent for fatty acid detection in biological samples.


Preparation of crystalline esters from acids

Safety & Documentation

Safety Information

GHS05  GHS05
Signal word 
Hazard statements 
Precautionary statements 
UN 2645 6.1 / PGII
WGK Germany 
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C


Certificate of Analysis


Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Do you have references on the use of 2-Bromoacetophenone (also known as phenacyl bromide) Products 115835 and 77450 for making phenacyl esters of carboxylic acids for HPLC analysis?
For information on the use of phenacyl bromide to derivatize carboxylic acids (e.g., fatty acids) for HPLC analysis, please see one or more of the following three references:1. K.J. Longmuir, et al., Determination of monoenoic fatty acid double bond position by permanganate-periodate oxidation followed by high-performance liquid chromatography of carboxylic acid phenacyl esters. Analytical Biochemistry, 167(2), 213-221 (1987).2. T. Hanis et al., Determination of fatty acids as phenacyl esters in rat adipose tissue and blood vessel walls by high-performance liquid chromatography. Journal of Chromatography, 452, 443-457 (1988). 3. A. Mehta et al., Rapid quantitation of free fatty acids in human plasma by high-performance liquid chromatography. Journal of Chromatography B Biomedical Science Applications, 719(1-2), 9-23 (1998).
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