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1-Methyl-2-pyrrolidinone

analytical standard

Synonym: 1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

  • CAS Number 872-50-4

  • Empirical Formula (Hill Notation) C5H9NO

  • Molecular Weight 99.13

  •  Beilstein/REAXYS Number 106420

  •  EC Number 212-828-1

  •  MDL number MFCD00003193

  •  PubChem Substance ID 329768179

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Alpha Sort, Analytical Standards, Analytical/Chromatography, Chemical Class,
Quality Level   100
grade   analytical standard
vapor density   3.4 (vs air)
vapor pressure   0.29 mmHg ( 20 °C)
  0.99 mmHg ( 40 °C)
assay   ≥99.9% (GC)
form   neat
autoignition temp.   518 °F
shelf life   limited shelf life, expiry date on the label
expl. lim.   9.5 %
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
refractive index   n20/D 1.47 (lit.)
  n20/D 1.470
bp   202 °C (lit.)
  81-82 °C/10 mmHg (lit.)
mp   −24 °C (lit.)
density   1.028 g/mL at 25 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Environmental
Food and Beverages
Personal Care
format   neat
SMILES string   CN1CCCC1=O
InChI   1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
InChI key   SECXISVLQFMRJM-UHFFFAOYSA-N

Description

General description

1-Methyl-2-pyrrolidinone is a polar solvent widely used in organic chemistry and polymer chemistry. On a large scale, it finds applications in the recovery and purification of acetylenes, olefins, and diolefins, gas purification, and aromatics extraction from feedstocks.

Application

1-Methyl-2-pyrrolidinone may be used as an eluent and extraction solvent for the extraction of soluble materials in soil samples using size exclusion chromatography.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory system
RIDADR 
NA 1993 / PGIII
WGK Germany 
WGK 1
RTECS 
UY5790000
Protocols & Articles

Articles

The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

Organic volatile impurities or “OVIs” sometimes remain behind in pharmaceutical preparations as a result of synthetic and manufacturing procedures. For reasons of health and safety, testing is done t...
Katherine Stenerson, Shyam Verma
Reporter US Volume 28.1
Keywords: Chromatography, Gas chromatography, Organic synthesis, Pharmaceutical, Solvents

Peer-Reviewed Papers
15

References

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