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82280 Sigma-Aldrich

1,2-Propanediol

puriss. p.a., ACS reagent, ≥99.5% (GC)

Synonym: 1,2-PDO, Propylene glycol

  • CAS Number 57-55-6

  • Linear Formula CH3CH(OH)CH2OH

  • Molecular Weight 76.09

  •  Beilstein/REAXYS Number 1340498

  •  EC Number 200-338-0

  •  MDL number MFCD00064272

  •  PubChem Substance ID 57652909

  •  NACRES NA.21

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Properties

Related Categories Analytical Reagents, Analytical Reagents for General Use, Analytical/Chromatography, O-P, Puriss p.a. ACS, Puriss p.a. ACS More...
Quality Level   200
grade   ACS reagent
vapor density   2.62 (vs air)
vapor pressure   0.08 mmHg ( 20 °C)
grade   puriss. p.a.
assay   ≥99.5% (GC)
form   viscous liquid
autoignition temp.   779 °F
shelf life   3 yr
expl. lim.   12.5 %
impurities   ≤0.003% free acid (as CH3COOH)
  ≤0.1% water
evapn. residue   ≤0.005%
ign. residue   <0.005% (as SO4)
refractive index   n20/D 1.432 (lit.)
  n20/D 1.433
bp   187 °C (lit.)
mp   −60 °C (lit.)
density   1.036 g/mL at 25 °C (lit.)
anion traces   chloride (Cl-): ≤1 mg/kg
  sulfate (SO42-): ≤20 mg/kg
cation traces   Ca: ≤5 mg/kg
  Cd: ≤1 mg/kg
  Co: ≤1 mg/kg
  Cr: ≤1 mg/kg
  Cu: ≤1 mg/kg
  Fe: ≤1 mg/kg
  K: ≤20 mg/kg
  Mg: ≤1 mg/kg
  Mn: ≤1 mg/kg
  Na: ≤20 mg/kg
  Ni: ≤1 mg/kg
  Pb: ≤1 mg/kg
  Zn: ≤5 mg/kg
SMILES string   CC(O)CO
InChI   1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
InChI key   DNIAPMSPPWPWGF-UHFFFAOYSA-N

Description

General description

1,2-Propanediol is a 1,2-alkanediol. It can be obtained from glycerol, via hydrogenolysis in the presence of Ru/C and Amberlyst ion-exchange resins.

Application

1,2-Propanediol (propanediol) may be employed as a cryoprotective agent for the preservation (by cooling to sub-zero temperatures) of human embryos and oocytes (human and mouse).

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 82280.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
TY2000000
Flash Point(F) 
219.2 °F - closed cup
Flash Point(C) 
104 °C - closed cup
Protocols & Articles

Articles

GC Analysis of 1,2-Alkyldiol Enantiomers (O-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX® G-TA

From our library of Articles, Sigma-Aldrich presents GC Analysis of 1,2-Alkyldiol Enantiomers (O-Trifluoroacetyl Derivatives) on Astec® CHIRALDEX® G-TA
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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