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85882 Sigma-Aldrich

Streptozocin

≥98.0% (HPLC)

Synonym: N-(Methylnitrosocarbamoyl)-α-D-glucosamine, Streptozotocin

  • CAS Number 18883-66-4

  • Empirical Formula (Hill Notation) C8H15N3O7

  • Molecular Weight 265.22

  •  Beilstein Registry Number 2060675

  •  EC Number 242-646-8

  •  MDL number MFCD00006607

  •  PubChem Substance ID 329769421

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Properties

InChI Key   ZSJLQEPLLKMAKR-GKHCUFPYSA-N
assay   ≥98.0% (HPLC)
mp   121 °C (dec.)(lit.)
Mode of action   DNA synthesis | interferes
storage temp.   −20°C

Description

Biochem/physiol Actions

An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage. Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.

Other Notes

This product has been replaced by S0130-SIGMA | Streptozocin ≥75% α-anomer basis, ≥98% (HPLC), powder

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
LZ5775000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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replaced by

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Description

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S0130 Streptozocin, ≥75% α-anomer basis, ≥98% (HPLC), powder

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