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Betulinic acid

analytical standard

Synonym: 3β-Hydroxy-20(29)-lupaene-28-oic acid, Lupatic acid, Mairin

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Properties

Related Categories A - D, Additional Standards, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography,
grade   analytical standard
InChI Key   QGJZLNKBHJESQX-FZFNOLFKSA-N
assay   ≥97.0% (HPLC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
mp   295-298 °C (dec.) (lit.)
Featured Industry   Food and Beverages
format   neat
storage temp.   2-8°C

Description

Biochem/physiol Actions

Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Betulinic acid may be used as a reference standard in the determination of betulinic acid in white birch bark using reversed-phase high-performance liquid chromatography (RP-HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Betulinic acid is a pentacyclic triterpene, isolated from the leaves of Syzigium claviflorum. It is found to be an inhibitor of HIV replication in H9 lymphocyte cells.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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