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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Flavonoids, Phytochemical Standards
Quality Level   100
grade   analytical standard
assay   ≥95.0% (HPLC)
shelf life   limited shelf life, expiry date on the label
mp   210-213 °C (lit.)
Featured Industry   Food and Beverages
SMILES string   COc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O
InChI   1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3
InChI key   WUADCCWRTIWANL-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Biochanin A is an isoflavone phytoestrogen found in red clover (Trifolium pratense) that is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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