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92301 Millipore

Listeria mono Selective Supplement I

for microbiology

Synonym: Listeria monocytogenes Selective Supplement I, Polymyxin B sulfate salt

  • CAS Number 1405-20-5

  • Empirical Formula (Hill Notation) C55H96N16O13 · 2H2SO4

  • Molecular Weight 1385.61

  •  EC Number 215-774-7

  •  MDL number MFCD00131991

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Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application,
grade   for microbiology
shelf life   limited shelf life, expiry date on the label
Featured Industry   Environmental
Food and Beverages
Mode of action   cell membrane | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
  fungi
storage temp.   2-8°C
suitability   Listeria

Description

Components

(per vial, sufficient for 500 ml medium)
Polymyxin B sulphate 38350 IU

Biochem/physiol Actions

Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides†, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.

Antimicrobial spectrum: Has bactericidal action on most gram-negative bacilli††, including E. Coli and on most fungi and gram-positive bacteria.

General description

A selective supplement recommended by ISO Committee for the isolation of Listeria species.

Chemical structure: peptide

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
TR1150000
Protocols & Articles

Articles

Microbiology Introduction

An initial aim of all microbiologists is the reproducible growth of their microbial cultures, no matter whether the microorganisms are of natural origin or have been genetically engineered by man. Re...
Keywords: Absorption, Aerobic, Anaerobic, Antibiotics, Antimicrobials, Buffers, Culture media, Diffusion, Environmental, Filtration, Genetic, Growth factors, Metabolism, Phase transitions, Precipitation, Reductions, Respiration, Sample preparations, Vitamins

Microbiology Theory: Media Preparation

Microorganisms need nutrients, a source of energy and certain environmental conditions in order to grow and reproduce. In the natural environment, microbes have adapted to the habitats most suitable ...
Keywords: Culture media, Digestions, Environmental, Filtration, Growth factors, Indicators, Microbiology, Phase transitions, Precipitation, Vitamins

Peer-Reviewed Papers
15

References

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