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N-Propionylglycine

analytical standard

Synonym: 2-(Propionylamino)acetic acid, N-(1-Oxopropyl)glycine, NSC 158539, Propionyl glycine

  • CAS Number 21709-90-0

  • Empirical Formula (Hill Notation) C5H9NO3

  • Molecular Weight 131.13

  •  Beilstein/REAXYS Number 1759032

  •  MDL number MFCD09049674

  •  NACRES NA.24

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Properties

Quality Level   100
grade   analytical standard
assay   ≥98.0% (HPLC)
shelf life   limited shelf life, expiry date on the label
storage temp.   2-8°C
SMILES string   OC(CNC(CC)=O)=O
InChI   1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)
InChI key   WOMAZEJKVZLLFE-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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