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95054 Supelco

Azelaic acid

analytical standard

Synonym: Nonanedioic acid

  • CAS Number 123-99-9

  • Linear Formula HO2C(CH2)7CO2H

  • Molecular Weight 188.22

  •  Beilstein/REAXYS Number 1101094

  •  EC Number 204-669-1

  •  MDL number MFCD00004432

  •  PubChem Substance ID 329770414

  •  NACRES NA.24

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Properties

Related Categories A-F, A-L, Additional Standards, Alcoholic & Nonalcoholic Beverages, All Alphabetically Sorted,
Quality Level   100
grade   analytical standard
vapor density   6.5 (vs air)
vapor pressure   <1 mmHg ( 20 °C)
assay   ≥98.5% (GC)
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
impurities   ≤0.5% water
bp   286 °C/100 mmHg (lit.)
mp   106-112 °C
  109-111 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Flavors and Fragrances
Food and Beverages
Personal Care
format   neat
SMILES string   OC(=O)CCCCCCCC(O)=O
InChI   1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
InChI key   BDJRBEYXGGNYIS-UHFFFAOYSA-N

Description

General description

Azelaic acid (heptane-l,7-dicarboxylic acid), a dicarboxylic saturated acid, is an active component of some topical anti-acne preparations. It is reportedly identified in cosmetics and pharmaceuticals. Azelaic acid is found to suppress the growth of Propionibacterium spp. and reduce keratinization.

Application

Azelaic acid may be used as an analytical reference standard for the quantification of the analyte in the following:
• Tobacco using gas chromatography coupled to mass spectrometry (GC-MS).
• Topical preparations using reversed-phase liquid chromatographic (LC) with UV-Vis detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
CM1980000
Flash Point(F) 
410.0 °F - closed cup
Flash Point(C) 
210 °C - closed cup
Protocols & Articles

Articles

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Peer-Reviewed Papers
15

References

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