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PHR1777 Sigma-Aldrich

Orphenadrine Citrate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: β-Dimethylaminoethyl 2-methylbenzhydryl ether citrate salt, o-Methyldiphenhydramine citrate salt, Orphenadrine citrate salt

  • CAS Number 4682-36-4

  • Empirical Formula (Hill Notation) C18H23NO · C6H8O7

  • Molecular Weight 461.50

  •  MDL number MFCD00079197

  •  PubChem Substance ID 329823606



Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Pharmaceutical Secondary Standards,
grade   certified reference material
  pharmaceutical secondary standard
packaging   pkg of 1 g
pharmacopeia traceability   traceable to PhEur Y0000101
  traceable to USP 1479009


Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Biochem/physiol Actions

Muscarinic receptor antagonist; H1 histamine receptor antagonist; muscle relaxant. Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Other Notes

This product was designed, produced and verified for accuracy and stability in accordance with ISO/IEC 17025:2005 (ANAB Cert AT-1467), ISO GUIDES 34:2009 (ANAB Cert AR-1470).


To see an example of a Certificate of Analysis for this material enter LRAA8433 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.


Certificate of Analysis

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