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Ascorbic acid

European Pharmacopoeia (EP) Reference Standard

Synonym: L-Ascorbic acid, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

  • CAS Number 50-81-7

  • Empirical Formula (Hill Notation) C6H8O6

  • Molecular Weight 176.12

  •  Beilstein/REAXYS Number 84272

  •  EC Number 200-066-2

  •  MDL number MFCD00064328

  •  PubChem Substance ID 329770703

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards A - B, Pharmacopeia & Metrological Institutes Standards More...
biological source   synthetic
grade   pharmaceutical primary standard
Agency/Method   EP Reference standard
form   neat
mfr. no.   EDQM
mp   190-194 °C (dec.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
storage temp.   2-8°C
SMILES string   OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
InChI   1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key   CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Ascorbic acid or vitamin C is a water-soluble vitamin found in various foodstuffs. The benefits of vitamin C may include protection against immune system deficiencies and cardiovascular disease, hyperpigmentation treatment, skin protection, anti-aging, iron absorption, and RBC production. It is used to treat scurvy, and it also functions as an antioxidant. Vitamin C is useful in the biosynthesis of collagen, L-carnitine, and neurotransmitters.

Application

Ascorbic acid may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrophotometric techniques.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
CI7650000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Assay and Organic Impurity Profiling of Droxidopa using a ZIC-HILIC column and UV detection

Droxidopa is a synthetic amino acid precursor, and acts as a prodrug to norepinephrine (noradrenaline) to increase neurotransmitter concentration in the body and the brain. Droxidopa was developed by...
Keywords: High performance liquid chromatography, Neurotransmitters, Pharmaceutical

HILIC Analysis of Polar Vitamins on Ascentis® Express OH5

From our library of Articles, Sigma-Aldrich presents HILIC Analysis of Polar Vitamins on Ascentis® Express OH5
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Ascorbic Acid on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ascorbic Acid on Ascentis® RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Water Soluble on Discovery® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble on Discovery® C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Vitamins, Water Soluble, on Discovery® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble, on Discovery® C8
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Vitamins, Water Soluble, on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Vitamins, Water Soluble, on Discovery® RP-Amide C16
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water Soluble Vitamins on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water Soluble Vitamins on Ascentis® RP-Amide
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

Peer-Reviewed Papers
15

References

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PHR1008 Ascorbic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
08168 Timestrip Plus 8 °C

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